Happy to see our paper “SECNVs: A Simulator of Copy Number Variants and Whole-Exome Sequences From Reference Genomes” published in Frontiers in Genetics! A robust CNV simulator for exome data was sorely needed, and we think SECNVs is filling this gap nicely. We included a number of options in this tool that will help customize CNV and exome read simulations to test current and novel algorithms to detect CNVs.
It was a pleasure working with co-authors Yue Xing, Alan Dabney, Xiao Li, Guosong Wang and Clare Gill on this project. Yue Xing, who was a PhD student in the Genetics program when we started this work, deserves a lot of credit for her contribution to this work.