Phage therapy back in the news

An alternative treatment for antibiotic-resistant infections that are raising concern nationwide already exists. But there’s a big problem. The treatment is not approved for use in the United States.

And it could be a decade or more for the treatment, long used in Russia, former Soviet nations, Eastern Europe and more recently in Asian nations, before it gets regulatory approval for safety and effectiveness.

The treatment method involves bacteriophages — viruses that kill bacteria — that are the world’s most abundant organisms. Each phage injects DNA into a specific bacterium to replicate itself, killing the bacterium in the process.

Recently, the U.S. Centers for Disease Control and Prevention sounded a national alarm about “Superbugs” or CRE — carbapenem-resistant Enterobacteriaceae. The “nightmare bacteria” are becoming untreatable to a point of killing one of every two patients whose infections reach the bloodstream, the CDC states.

Bacteriophages offer a way to fight resistant bacteria, but their use still awaits approval in the U.S. – Pittsburgh Post-Gazette.

See related stories:

Intralytix develops and markets bacteriophage-based products
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Not all viruses are the bad guys – Pittsburgh Post-Gazette.

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