Vaccinations: When, What, & Why?
In this day and age, things have become complicated. We used to think all vaccinations were a good thing. Now, we have the “anti-vaxxers. “ Essentially, people who feel that vaccinations are not needed and may cause more harm than good. While, I’m not going to discuss human vaccinations, I will discuss sheep and goat vaccines. In particular, when to vaccinate and what to vaccinate for.
There is not much controversy in the sheep and goat community about the validity of vaccines. Most farmer/ranchers agree vaccines are a good thing. If vaccines are not used, it is because the disease causing pathogen is not prevalent or the vaccine is not effective at preventing disease, or the vaccination schedule is not feasible. But there has been some dispute as to when to vaccinate. In particular, can we vaccinate a lamb too early in life?
A recent journal article has been submitted for review in Translational Animal Science. This is a new research journal publication site that allows for public review and comments. The authors are Drs. Lewis, Taylor, and Wang and the research was conducted at the US sheep experiment station. The research is investigating when is the best time to vaccinate lambs for overeating, but has implication for other pathogens. Lambs are born without a fully functional immune system and require antibodies via the colostrum for protection for the first few weeks of life.
This research confirmed vaccination of ewes during gestation was effective at supplying antibodies to their lambs. This research also showed vaccinating these lambs at one day of age reduced antibodies in the lamb. The vaccine was likely tying up the antibodies provided by the mother via the colostrum. This could reduce the lamb’s ability to fight a disease. The day one vaccine with a booster two weeks later was effective at simulating the lamb’s immune system to develop its own antibodies. The research also confirmed a booster vaccine at weaning (5 months of age) was effective at increasing antibodies of previously vaccinated lambs. Interestingly, the booster response was higher for lambs previously vaccinated at 28 and 42 days of age versus 1 and 15 days of age. This open review research article can be found at: https://www.animalsciencepublications.org/publications/tas/open-review Give it a look and a review if you like.
Based on this, I’d recommend vaccinating ewes during late gestation and vaccinating lambs around one month of age with a booster at weaning. Don’t vaccinate lambs during their first week of life, because this is a critical time for their survival and vaccinating may reduce passive immunity in the short-term.
This research is primarily referencing vaccination for overeating or Clostridium perfringens. Overeating, plus tetanus, is the most common vaccines used for sheep and goats. There are a wide variety of other diseases to vaccinate against. I’ll touch on a couple of them that are common in Texas.
Sore mouth vaccine is a live virus. It is normally given to sheep and goats at marking/docking. Since it is a live virus, there is no need to provide a booster. Humans can develop the disease, so wear gloves when vaccinating animals or treating infected animals. The vaccine should not be used on farm/ranches that have no history of the disease. It does not transfer immunity from dam to offspring, so vaccinating females during gestation does not help the offspring.
Caseous lymphadenditis, CL or cheesy gland, is a disease common in sheep and goats. Animals develop internal and external abcesses in the lymph nodes. It is highly contagious and causes chronic issues when the disease advances. The pathogen does not cause acute disease symptoms, so often animals are culled and the flocks/herds are not vaccinated. There is an effective vaccine for sheep, produced by Colorado Serum, and goats, produced by Texas Vet Labs. The vaccine should be given to replacement animals to prevent them from acquiring the disease. The vaccine does not help infected animals.
Aborting diseases are another common issue for sheep and goats. The top aborting diseases in sheep and goats that can be vaccinated against are Chlamydia, Vibrio (EAE), and Leptospirosis. These diseases typically occur when new females are brought into an operation and naïve animals are exposed to the disease. The vaccines tend to be strain specific.
I’d be remiss if I did not discuss vaccination methods. First of all, vaccinations should be given in the label-approved route of administration. Most vaccines are to be used as a sub-cutaneous injection. Avoid intramuscular injections, if possible, because they could result in meat abscesses. Consider changing needles between animals or groups of animals, especially for adults. It is counter productive to give a vaccine for one disease but spread another disease (like ovine progressive pneumonia or caseous lymphadenitis) in doing so. For large operations, I realize that it may seem impractical but it may be cost effective to use a needleless (pneumatic) vaccination device.
As we discuss animal health and vaccines, it is very important managers of sheep and goats develop a relationship with their veterinarian. Veterinarians are excellent resources for animal health. In addition, small ruminants can be limited to what products are available over the counter. Extra-label drug use is common for sheep and goats but your veterinarian must prescribe it.
Does every sheep and goat operation need to vaccinate? No. But vaccines are a cheap and effective method to prevent diseases that cannot be prevented with management strategies.
To provide feedback on this article or request topics for future articles, contact me at reid.redden@ag.tamu.edu or 325-653-4576.