Genetics 302 – Honors

General Information

Syllabus-302H – Fall 2013

Fall 2013

Instructor: John R. Gold

Office: 324A, Old Heep Building    Voice: 979-847-8778    Internet: goldfish@tamu.edu

Office Hours: By Appointment (a phone call or electronic message will do)

Lecture: MWF, 9: 10- 10: 00 a.m., 308 Nagle

Lab: You must be registered for and attend the scheduled laboratory. Arrangements to make- up a missed laboratory session will be discussed by your Teaching Assistant( who also will discuss purchase of the laboratory text). Laboratory may or may not convene during the first week of class. Your lab section is 201 and it meets on Wednesdays from 10: 20 am to 1: 10 pm in BICH 244.

Textbooks:

Lecture: Essential Genetics, D. L. Hard [ 5`h Edition, paperback]
Laboratory: Genetics Laboratory Exercises
Syllabus and Lecture Notes: http://agrilife.org/gold/courses/genetics-302-honors/

Grades: Your grade will be determined as follows: 80% from material comprising four major exams. The laboratory will count 20% of your grade. Note that exams during the semester are in the evening and on Wednesdays.

Exam Schedule:

Exam#1 – Wednesday, September 18 6:15 – 7.30 pm Weeks 1 – 3
Exam #2 – Wednesday, October 9 6:15 – 7:30 pm Weeks 4 – 6
Exam #3 – Wednesday, November 6 6:15 – 7:30 pm Weeks 7 – 10
Final: Exam #4- Monday, December 9 8:00 – 10:00 am Weeks 11 – 14

Absences: Only an authorized absence will merit a make- up exam or quiz. Make-up exams are to be arranged with the instructor(s). The policy for make- up quizzes will be discussed by your Teaching Assistant.

Catalog Description: Fundamental principles of genetics: physical basis of Mendelian inheritance, expression, and interaction of genes, linkage, sex linkage, biochemical nature of genetic material and mutation.

Prerequisites: BOTN 101, ZOOL 107, or BIOL 113.

Other: Handouts used in this course are copyrighted. Handouts include (but are not limited to) syllabi, quizzes, exams, lab problems, and in-class materials. Because these materials are copyrighted, you do not have the right to copy handouts  unless specifically given permission by the instructor. Doing so, i. e., copying handouts,  constitutes plagiarism. If you have any questions, please consult the latest issue of the Texas A& M University Student Rules, under the section Scholastic Dishonesty.

The American with Disabilities Act( ADA) is a federal anti- discrimination statute that provides comprehensive civil rights protection for persons with disabilities. Among other things, this legislation requires all students with disabilities be guaranteed a learning environment that provides for reasonable accommodation of their disabilities. If you believe you have a disability requiring an accommodation, please contact the Department of Student Life for Students with Disabilities in Room 126 of the Koldus Building, or call 845- 1637.

SUGGESTED READING 

GENETICS 302H – Fall 2013

Note: Chapter 1 is an overview of many things you’ve already learned and of topics to be discussed in several parts of the course. Please read the chapter in its entirety as a means to prepare for the course.

Lecture topics
Reading
Week 1
(Aug. 26 – Aug. 30)
Introduction and history; segregation and independent assortment;
multiple alleles; types of dominance
Chapter 2, p. 35-48, 54-58;
Chapter 3, p. 69-81
Week 2
(Sept. 2 – Sept. 6)
Probability and binomial expansion (brief);
X2 goodness-of-fit tests;
pedigree analysis;
gene interaction and epistasis
Chapter 2, p. 48-54, p. 58-59;
Chapter 3, p. 99-105;
Chapter 2, p. 59-63
Week 3
(Sept. 9 – Sept. 13)
Sex chromosomes and sex linkage;
nondisjunction;
sex effects and sex determination;
types of sexuality
Chapter 3, p. 92-98;
Chapter 5, p. 155-166;
Chapter 9, p. p. 316-317
Week 4
(Sept. 16 – Sept. 20)
Gene and genotype frequencies;
H-W equilibrium;
inbreeding;
Exam #1
Chapter 14, p. 467-493;
Chapter 4, p. 131-133
Week 5
(Sept. 23 – Sept. 27)
Forces that change gene frequency;
quantitative inheritance
Chapter 15, p. 498-513;
Chapter 15, p. 516-520
Week 6 (Sept. 30 – Oct. 4) Linkage and recombination;
gene mapping in eukaryotes and bacteria
Chapter 4, p. 111-128;Chapter 7, p. 223-243, p. 248-254
Week 7
(Oct. 7 – Oct. 11)
DNA/RNA structure;
chromosome;
structure;
genome organization; Exam #2
Chapter 6, p. 189-195;
Chapter 3, p. 81-92
Week 8
(Oct. 14 – Oct. 18)
Repeated DNA;
DNA replication;
RNA synthesis and processing
Chapter 12, p. 408-409;
Chapter 6, p. 195-209;
Chapter 8, p. 260-273
Week 9
(Oct. 21 – Oct. 25)
Translation and the genetic code;
mutation and mutagenesis
Chapter 8, p. 273-289;
Chapter 12, p. 396-404, 407-421
Week 10
(Oct. 28 – Nov. 1)
DNA repair;
transposable elements;
organelle genetics
Chapter 12, p. 421-426, 404-409;
Chapter 7, p. 224-226;
Chapter 14, p. 490-493
Week 11
(Nov. 4 – Nov. 8)
Gene regulation in prokaryotes;
Gene regulation in eukaryotes; Exam #3
Chapter 9, p. 294-306, 310-324
Week 12
(Nov. 11 – Nov. 15)
Genetics of cancer;
guest lecture on AIDS;
Chapter 13 (General reading)Chapter 15, p. 151 – 155, 166 – 173
Week 13
(Nov. 18 – Nov. 22)
Inversions and translocations; Other types of chromosomal rearrangement; Chapter 5, p. 173 – 177Chapter 4, p. 133 – 134
Week 14
(Nov. 25 – Nov. 27)
aneuploidy and polyploidy Chapter 5, p. 161 – 166, 177 – 183
Week 15 (Dec. 2) Evolutionary consequences of chromosomal rearrangement No suggested reading

Lecture Outlines

Lecture 1 – PDF Lecture 2 – PDF Lecture 3 – PDF Lecture 4 – PDF Lecture 5 – PDF
Lecture 6 – PDF Lecture 7 – PDF Lecture 8 – PDF Lecture 9 – PDF Lecture 10 – PDF
Lecture 11 PDF Lecture 12 – PDF Lecture 13 – PDF Lecture 14 – PDF Lecture 15 – PDF
Lecture 16 – PDF Lecture 17 – PDF Lecture 18 – PDF Lecture 19 – PDF Lecture 20 – PDF
Lecture 21 – PDF Lecture 22 – PDF Lecture 23 – PDF Lecture 24 – PDF Lecture 25 – PDF
Lecture 26 – PDF Lecture 27 – PDF Lecture 28 – PDF Lecture 29 – PDF Lecture 30 – PDF
Lecture 31 – PDF Lecture 32 – PDF Lecture 33 – PDF Lecture 34 – PDF Lecture 35 – PDF

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